Embryogen is suitable for all patients, and especially recommended for patients who have experienced recurrent miscarriage, recurrent implantation failures or unexplained infertility.
Embryogen is a culture medium that have been developed with the addition of the cytokine Granulocyte Macrophage Colony Stimulating Factor (GM-CSF).
What is Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
GM-CSF is the active ingredient in Embryogen.
GM-CSF is a protein expressed in the female reproductive tract and upregulated throughout embryo development. Research has shown that an addition of 2ng/ml GM-CSF to culture media improved embryo growth and development.
GM-CSF appears to assist embryo development in several ways:
- regulates cell survival, proliferation and differentiation
- regulates immune response
- important for cell signaling
- important for cell to cell communication
- promotes blastocyst formation
- preimplantation embryos express receptors for GM-CSF
- participates in the regulation of implantation.
