Assisted reproductive technologies (ARTs) are very important tools to deal with infertility problems which affect almost 50 million couples around the world. It is estimated that about half of couples’ infertility cases are attributed to male infertility, hence poor sperm quality or insufficient concentration of spermatozoa. This is why sperm selection is crucial for its use in ARTs such as in vitro fertilization (IVF), intra-cytoplasmic sperm injection (ICSI) and intrauterine insemination (IUI).
Microfluidics provides the appropriate tools to solve issues with current ARTs, from sperm selection to artificial fertilization, in a more democratic and less invasive way.
Microfluidic systems are also able to mimic closely in vivo conditions of sperm selection.
Source- https://www.elveflow.com/microfluidic-reviews/microfluidics-for-cell-biology/microfluidic-for-sperm-sorting-a-review/